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Physical therapy is usually a component of treatment for patients of Parkinson’s disease and other neurodegenerative and motor system disorders.

Now, a ������ professor in the College of Education, Health and Human Services has designed a piece of equipment that serves that purpose and sets the bar for exercise therapy higher.

Angela Ridgel, Ph.D., an associate professor of exercise science and an avid cyclist, has designed a bicycle specially tailored to Parkinson’s patients. The bike is based on a tandem bicycle model – a bike ridden by two people.

She and Jay Alberts, Ph.D., the Bell Family Endowed Chair in the Department of Biomedical Engineering at the Cleveland Clinic Lerner Research Institute, came up with the idea. Alberts, also a cyclist, told Ridgel of a tandem ride he was on with a cyclist who suffered from Parkinson’s.

“She told him that when she rides on a tandem with him, she doesn’t feel like she has Parkinson’s,” Ridgel says.

Ridgel says that is because cyclists try to maintain a high pedal cadence, and in tandem riding, one cyclist drives the cadence for the other one.

Ridgel says speed made the difference.

“We’re retraining the nervous system to work faster and more efficiently,” she says.

Improvement in Patients

Working with Alberts while she was still a postdoctoral research fellow at Cleveland Clinic, they brought in Parkinson’s patients to train on a tandem bike three times a week for eight weeks.

The patients saw a 30 percent improvement in symptoms like tremors and slowness of movement, compared to a control group that trained with no pacing.

“The trainer does most of the work,” she says. “The patients only put in about 25 percent of the effort and didn’t perceive it as strenuous.”

When she came to ������, Ridgel says, “I wanted to design a motorized bike that could do this.”

A 2012 National Institutes of Health grant gave Ridgel the green light to continue the work and test her model with the help of Case Western Reserve University and Rockwell Automation, which provided the motor system and technology.

The computer-driven bike reacts to the patient’s progress and records the results, then adjusts the exercise regimen to help that specific patient progress.

“It dynamically alters the set speed to create the variation in cadence like you’d have on an actual tandem bike ride, that is necessary to yield improvement results, which is really unique,” Ridgel says. “Nobody else has done that.”

Undergoing three sessions of 40 minutes each, patients’ symptoms were monitored based on the Unified Parkinson’s Disease Rating Scale.

Ridgel says the patients using the dynamic cadence model averaged about 78.6 revolutions per minute (rpm) versus the static 66 rpm. Even though they were going at a higher cadence, the dynamic group’s power rating averaged only about 8.2 compared to the 31.2 of the static group, and their heart rates hovered around 91 beats per minute (bpm) versus the 103 bpm of the static patients. Dynamic group patients even felt like they were exerting less effort despite the higher cadence — rating it from 1-20, patients cycling at the dynamic cadence rated exertion on average at 12.7, compared to 13.6 among static (lower) cadence patients.

The Need for Further Research

Ridgel says the grant has run out, but the numbers clearly show that the research should continue.

While the treatment is not “one-size-fits-all,” she says that with further research, trainers could determine and even predict what exercise regimen an individual patient would need.

She says the results from the Parkinson’s study have major implications for possible treatment among patients suffering from other ailments, such as stroke or multiple sclerosis.

“We’re retraining the nervous system to work more efficiently, so we can use that paradigm to work on any neurological condition,” she says. “We have the data. We just need the money.”

For more information about Ridgel and her work, visit www.kent.edu/ehhs/hs/profile/angela-ridgel-phd.

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